Abstract KRAS mutations are broadly recognized as promising targets for tumor therapy.T cell receptors (TCRs) can specifically recognize KRAS mutant neoantigens travc presented by human lymphocyte antigen (HLA) and mediate T cell responses to eliminate tumor cells.In the present study, we identify two TCRs specific for the 9-mer KRAS-G12V mutant ne
Women are underrepresented in many areas of journalistic pedro sauer seminar curran martial arts newsrooms.In this paper, we examine if this established effect persists in the new forms of journalistic communication, namely social media networks.We use mentions, retweets, and hashtags as measures of journalistic amplification and legitimation.Furth
The glyoxalase system is a ubiquitous cellular metabolic pathway whose main physiological role is the removal of methylglyoxal (MG).MG, a glycolysis byproduct formed by the spontaneous degradation of triosephosphates glyceraldehyde-3-phosphate (GA3P) and dihydroxyacetonephosphate (DHAP), is an arginine-directed glycating agent and precursor of the
Oral maxillofacial rehabilitation of the atrophic maxilla with or without pneumatization of the maxillary sinuses routinely presents limited bone availability.This indicates the need for vertical and horizontal bone augmentation.The standard and most used technique is maxillary sinus augmentation using distinct techniques.These techniques may or ma
Stinging nettle (Urtica dioica) is a plant well known in traditional medicine for its many beneficial properties, but the lack of standardization regarding the product to offer to consumers limits its diffusion.To this end, drying appears to be a useful technique to offer a low-cost product that can be stored for long time, but the different drying